SAM D21 Arm® Cortex®-M0+ Microcontrollers

Microchip Technology SAM D21 Arm® Cortex®-M0+ Microcontrollers (MCUs) are low-power MCUs that range from 32- to 64-pins with up to 256KB Flash and 32KB of SRAM. The Microchip Technology SAM D21 MCUs have a maximum 48MHz frequency and reach 2.46 CoreMark/MHz. The devices are designed for simple and intuitive migration with identical peripheral modules. Features include hex-compatible code, identical linear address map, and pin-compatible migration paths between all devices in the product series. All devices include intelligent and flexible peripherals, an Event System for inter-peripheral signaling, and support for capacitive touch buttons, slider, and wheel user interfaces.

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Description Datasheet Availability Pricing (RON) Filter the results in the table by unit price based on your quantity.
Qty. RoHS ECAD Model Series
Mounting Style
Package/Case
Core
Program Memory Size
Data Bus Width
ADC Resolution
Maximum Clock Frequency
Number of I/Os
Data RAM Size
Supply Voltage - Min
Supply Voltage - Max
Minimum Operating Temperature
Maximum Operating Temperature
Qualification
Packaging
Microchip Technology ARM Microcontrollers - MCU CM0,TQFP32, 64kFlash,Tray,USB,Extended Temp
Datasheet
744In Stock
Min.: 1
Mult.: 1

SMD/SMT TQFP-32 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 26 I/O 8 kB 1.62 V 3.63 V - 40 C + 125 C Tray

Microchip Technology ARM Microcontrollers - MCU 32QFN,125C TEMP, GREEN, 5V, 48MHZ, Tray
Datasheet
445In Stock
Min.: 1
Mult.: 1

SMD/SMT VQFN-32 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 26 I/O 32 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 64TQFP,125C TEMP, GREEN, 1.6-3.6V, 48MHZ, Tray
Datasheet
286In Stock
Min.: 1
Mult.: 1

SMD/SMT TQFP-64 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 52 I/O 32 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray

Microchip Technology ARM Microcontrollers - MCU CM0,QFN32, 128kFlash,Trays,USB,Extended Temp
Datasheet
490In Stock
Min.: 1
Mult.: 1

SMD/SMT VQFN-32 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 26 I/O 16 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU CM0,QFN64, 128kFlash,Trays,USB,Extended Temp
Datasheet
240In Stock
Min.: 1
Mult.: 1

SMD/SMT VQFN-64 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 52 I/O 16 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU CM0,TQFP32, 128kFlash,Trays,USB,Extended Temp
Datasheet
470In Stock
Min.: 1
Mult.: 1

SMD/SMT TQFP-32 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 26 I/O 16 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU CM0,TQFP48, 64kFlash,Tray,USB,Extended Temp
Datasheet
409In Stock
Min.: 1
Mult.: 1

SMD/SMT TQFP-48 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 38 I/O 8 kB 1.62 V 3.63 V - 40 C + 125 C Tray
Microchip Technology ARM Microcontrollers - MCU CM0,TQFP48, 128kFlash,Trays,USB,Extended Temp
Datasheet
299In Stock
Min.: 1
Mult.: 1

SMD/SMT TQFP-48 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 38 I/O 16 kB 1.62 V 3.63 V - 40 C + 125 C Tray
Microchip Technology ARM Microcontrollers - MCU CM0,TQFP64, 64kFlash,Tray,USB,Extended Temp
Datasheet
319In Stock
Min.: 1
Mult.: 1

SMD/SMT TQFP-64 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 52 I/O 8 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU CM0,TQFP64, 128kFlash,Trays,USB,Extended Temp
Datasheet
262In Stock
320Expected 6/25/2026
Min.: 1
Mult.: 1

SMD/SMT TQFP-64 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 52 I/O 16 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 32TQFP,125C TEMP, GREEN, 5V, 48MHZ, Tray
Datasheet
199In Stock
Min.: 1
Mult.: 1

SMD/SMT TQFP-32 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 26 I/O 32 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 48QFN,125C TEMP, GREEN, 5V, 48MHZ, Tray
Datasheet
359In Stock
Min.: 1
Mult.: 1

SMD/SMT VQFN-48 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 38 I/O 32 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray

Microchip Technology ARM Microcontrollers - MCU 256KB 32KB 64QFN GRN1.6-3.6V48MHz
Datasheet
13.536In Stock
MouseReel Available
Min.: 1
Mult.: 1
: 4.000

SAMD21 SMD/SMT QFN-64 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 52 I/O 32 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel

Microchip Technology ARM Microcontrollers - MCU 256KB 32KB 64QFN GRN1.6-3.6V48MHz
Datasheet
9.269In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT QFN-64 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 52 I/O 32 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU CM0, QFN 48 , 128KFlash, USB, Extended Temp 125C, Tray
Datasheet
5.543In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT VQFN-48 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 38 I/O 16 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 48TQFP 125C, GREEN,1.6-3.6V,48MHz
Datasheet
5.624In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT TQFP-48 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 38 I/O 32 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 64TQFP,125C TEMP, GREEN, 3.3V, 48MHZ,T&R
Datasheet
12.320In Stock
MouseReel Available
Min.: 1
Mult.: 1
: 1.500

SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 52 I/O 8 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 32TQFP 125C, GREEN,1.6-3.6V,48MHz
Datasheet
5.473In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT TQFP-32 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 26 I/O 32 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 32TQFP 125C, GREEN,1.6-3.6V,48MHz
Datasheet
9.389In Stock
MouseReel Available
Min.: 1
Mult.: 1
: 2.000

SAMD21 SMD/SMT TQFP-32 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 26 I/O 32 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 48QFN 125C, GREEN,1.6-3.6V,48MHz
Datasheet
14.217In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT QFN-48 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 38 I/O 32 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 32QFN,125C TEMP, GREEN, 3.3V, 48MHZ
Datasheet
2.718In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 32 kB 32 bit 12 bit 48 MHz 26 I/O 4 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 64TQFP,85C TEMP, GREEN, 3.3V, 48MHZ, T&R
Datasheet
2.956In Stock
MouseReel Available
Min.: 1
Mult.: 1
: 1.500

SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 32 kB 32 bit 12 bit 48 MHz 52 I/O 4 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 32QFN,85C TEMP, GREEN, 3.3V, 48MHZ
Datasheet
670In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 26 I/O 8 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 32TQFP 125C, GREEN,1.6-3.6V,48MHz
Datasheet
2.477In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT TQFP-32 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 26 I/O 16 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray

Microchip Technology ARM Microcontrollers - MCU CM0,TQFP32, 128kFlash,T&R,USB, I Temp
Datasheet
1.205In Stock
Min.: 1
Mult.: 1
: 2.000

SAMD21 SMD/SMT TQFP-32 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 26 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape